Well, in the history of mankind, no one has probably fully explored the capacities of the brain. But, it seems that Leonardo Da Vinci is the one who set the most inspiring example for those who wish to explore their fullest capacities. Since we are all gifted with an incomparable and unlimited potential for learning and creativity. Here is an expert from the Michael Gelb, who has made an attempt to codify the principles implicit in Leonardo's work. Below is the seven Da Vincian principles:

• Curiosity (Curiosita) - An insatiably curious approach to life and an unrelenting quest for continuous learning.
• Demonstration (Dimonstrazione) - A commitment to test knowledge through experience, persistence, and willingness to learn from mistakes.
• Sensation (Sensazione) - The continual refinement of the senses, especially sight, as the means to enliven experience.
• Smoke (Sfumato) - Becoming open to the unknown. A willingness to embrace ambiguity, paradox, and uncertainty.
• Art and Science (Arte/Scienza) - Whole-Brain thinking. The development of the balance between science and art, logic and imagination.
• The Body (Corporalita) - The cultivation of grace, ambidexterity, fitness, and poise. Balancing the body and mind.
• Connection (Connessione) - A recognition of and appreciation for the interconnectedness of all things and phenomena. Systems thinking.
• Here is the brief description of all the principles:
• Curiosita: Every human being does possess an innate sense of curiosity, which is very apparent from the tender age. As children, we are compelled to search for answers to things that we do not understand. A child understands that the questions are fundamental in the development of his knowledge base. Individuals who want to expand their base of knowledge, they are always open to the concept that conventional ways of doing things can be modified.
• Dimonstrazione: Human beings do have a willingness to learn from their mistakes. A mistake is being seemed as an experience, and experience is the best teacher. Our experiences provide a unique kind of knowledge. The combination of knowledge and experience provides a means for people to come up with hypotheses that may or may not be accurate when they test them out.
• Sensazione: Human beings perceive their experiences through the senses. According to Leonardo Da Vinci, the average human “looks without seeing, listens without hearing, touches without feeling, eats without tasting, moves without physical awareness, inhales without awareness of odor or fragrance, and talks without thinking.” Continuous sensory development will enhance our experiences, which in turn will allow us to fully grasp the totality of the lessons being taught.
• Sfumato: This is very common that we in our quest for knowledge will face the unknown. But, young children are not willing to deal with the paradoxes of life. However, as we grow older, we become more comfortable with the idea that familiar things can be done in new and different ways.
• Arte/Scienza: According to Leonardo Da Vinci, science and art are indivisible. He was not only a scientist who studied art, but also an artist who studied science. He was a "whole-brain" thinker. The left hemisphere of the cerebral cortex processes logical and analytical thinking, while the right hemisphere processes imaginative, big-picture thinking. But, modern educational systems emphasize left-brain thinking and neglect the right hemisphere. The result is that people who do well in school, but lack in creativity. And people who are dominated by their right-brain are often called as "learning disabled". This approach fails to appreciate that an individual who is capable of using both their left and right hemispheres are the ones who are truly intelligent. The notion that individuals who are outstanding left-brain thinkers are the most intelligent is a narrow minded perspective according to this principle.
• Corporalita: It says, good physical health has positive effects on our attitudes and emotions. Means, if the mind does not work, then the body does not work as well and vice versa!
• Connessione: Leonardo Da Vinci never provided a table of contents, an outline, or an index for any of his writings, his writings were written at random. It proves that he had a sense for connectedness. He didn't need to organize his notes because he saw how everything was related to one another. Thus, you can always take up a way that was never done in your life, and it may prove more than what you had ever imagined.